Before bottling, wine may require blending, filtration, and use of antiseptics to combat microbe development. Often several casks containing the same wine will develop differences during aging, and blending is desirable to ensure uniformity. Wines that are slightly deficient in colour or acid may be blended with special wines as a means of correction. Blending frequently improves quality by adding to the complexity of the wine.

A final polishing filtration is required before bottling, and the amount of sulfur dioxide is adjusted, especially in sweet table wines. Sulfur dioxide is frequently used, but sorbic acid or sorbates are used in sweet table wines to inhibit yeasts, although they are not generally recommended because of the off-odour that may develop. Such operations as the addition of sulfur dioxide, heating (wherever beneficial), and polishing filtration are usually accomplished by a continuous in-line process. Equipment, usually semiautomatic or completely automatic, must be free of undesirable microorganisms and is made of resistant alloys to avoid undesirable metal pickup.

During the actual bottling operation, oxygen pickup must be kept to a minimum. Bottomfilling--that is, inserting a tube into the bottle and filling from the bottom--is often used. In some cases, the bottle may be flushed with carbon dioxide before filling, or the wine may be sparged (agitated) with nitrogen gas. Wines subject to oxidation require special care.

Sterile new bottles are used in the United States. Elsewhere, bottles may be reused after thorough cleaning and sterilization. The bottle shape and colour are dictated by custom and cost. Some white wines, subject to change when exposed to light, are preferably bottled in brown, brownish green, or greenish blue coloured bottles. Although brown glass is probably preferable for Sauternes, custom dictates the use of clear bottles. Glass is still the usual material, although experiments have been made with plastics.

After bottling, the closure is made. Screw caps are used for standard wines. Cork closures are preferred for wines that will be aged in the bottle. Red wines that may be aged in the bottle for many years are closed with corks two inches (five centimetres) long or longer. Occasionally a cork may communicate an off-odour, called "corked," to the wine; this apparently results from a contaminant or from a defect that allows the growth of mold in or on the cork.

A capsule is placed over the closure, the label is applied, and the bottles are packaged in cases for shipment. Wines requiring bottle aging are often not capsuled, labeled, or cased until they have been aged.